Identifying people at a high risk of developing pancreatic cancer

Alison P. Klein

doi:10.1038/nrc3420

Identifying people at a high risk of developing pancreatic cancer

Alison P. Klein

School of Medicine

Research output: Contribution to journal › Review article › peer-review

97 Scopus citations

Abstract

Pancreatic cancer is a leading cause of cancer death, and it has the poorest prognosis of any major tumour type. Familial pancreatic cancer registries are important for investigating the genetic aetiology of this devastating disease. Using data from our familial pancreatic cancer registry and other registries, this Review discusses the usefulness of family registries in the study of pancreatic and other cancers, and also how such registries provide a unique opportunity for laboratory, population and clinical research.

Original language	English (US)
Pages (from-to)	66-74
Number of pages	9
Journal	Nature Reviews Cancer
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/nrc3420
State	Published - Jan 2013

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1038/nrc3420

Cite this

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title = "Identifying people at a high risk of developing pancreatic cancer",

abstract = "Pancreatic cancer is a leading cause of cancer death, and it has the poorest prognosis of any major tumour type. Familial pancreatic cancer registries are important for investigating the genetic aetiology of this devastating disease. Using data from our familial pancreatic cancer registry and other registries, this Review discusses the usefulness of family registries in the study of pancreatic and other cancers, and also how such registries provide a unique opportunity for laboratory, population and clinical research.",

author = "Klein, {Alison P.}",

note = "Funding Information: A special thank you to all of the patients and families who participate in the National Familial Pancreas Tumor Registry and other pancreatic cancer family studies without whom this research would not be possible. The author would also like to thank R. Hruban, K. Brune, E. Palmisano and D. Echavarria. A.P.K. receives support from the NCI SPORE in Gastrointestinal Cancer CA62924, RO1 CA154823 and the Sol Goldman Pancreatic Cancer Research Center.",

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N2 - Pancreatic cancer is a leading cause of cancer death, and it has the poorest prognosis of any major tumour type. Familial pancreatic cancer registries are important for investigating the genetic aetiology of this devastating disease. Using data from our familial pancreatic cancer registry and other registries, this Review discusses the usefulness of family registries in the study of pancreatic and other cancers, and also how such registries provide a unique opportunity for laboratory, population and clinical research.

AB - Pancreatic cancer is a leading cause of cancer death, and it has the poorest prognosis of any major tumour type. Familial pancreatic cancer registries are important for investigating the genetic aetiology of this devastating disease. Using data from our familial pancreatic cancer registry and other registries, this Review discusses the usefulness of family registries in the study of pancreatic and other cancers, and also how such registries provide a unique opportunity for laboratory, population and clinical research.

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Identifying people at a high risk of developing pancreatic cancer

Abstract

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