Abstract
A recent HIV-1 molecular epidemiology survey in Singapore identified a novel CRF01-AE/B recombinant form, which accounted for 13 (11.9%) of 109 patient samples. Peripheral blood mononuclear cell DNA from three of these 13 patients was used to generate near full-length sequences to characterize the novel CRF01-AE/B recombinant form. The three isolates had a recombinant structure composed of CRF01-AE and subtype B, and shared identical breakpoints. As the three patients were not epidemiologically linked, this recombinant form has been designated CRF51-01B. Identification of the novel recombinant forms indicates ongoing active HIV-1 transmission in Singapore.
Original language | English (US) |
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Pages (from-to) | 527-530 |
Number of pages | 4 |
Journal | AIDS research and human retroviruses |
Volume | 28 |
Issue number | 5 |
DOIs | |
State | Published - May 1 2012 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology
- Virology
- Infectious Diseases