Hyperthermic treatment of malignant diseases: Current status and a view toward the future

M. W. Dewhirst, L. Prosnitz, D. Thrall, D. Prescott, S. Clegg, C. Charles, J. MacFall, G. Rosner, T. Samulski, E. Gillette, S. LaRue

Research output: Contribution to journalReview articlepeer-review

139 Scopus citations


New studies in hyperthermia at the basic science, engineering, and clinical level have stimulated renewed enthusiasm for re-investigating its potential as an anti-cancer therapy. This article reviews the salient features of these recent results and points out areas for additional investigation. Highlighting these new results is the publication of several positive phase III trials for thermoradiotherapy compared to radiotherapy alone. Important highlights are the encouraging results using magnetic resonance imaging for noninvasive thermometry. If this technology is successfully implemented with real time power control it will revolutionize the clinical application of hyperthermia.

Original languageEnglish (US)
Pages (from-to)616-625
Number of pages10
JournalSeminars in oncology
Issue number6
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Hematology
  • Oncology


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