Hyperplasia of Brunner glands: The spectrum of its radiographic manifestations

Dimitri Merine, Bronwyn Jones, Gary G. Ghahremani, Stanley R. Hamilton, Theodore M. Bayless

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Radiographic features of the duodenal mucosa were analyzed in a series of 26 patients in whom the diagnosis of Brunner gland hyperplasis (BGH) had been established by endoscopic biopsies. The observed mucosal patterns could be classified into five categories: (1) focal BGH causing a solitary submucosal adenoma or a cluster of sessile polyps in the otherwise smooth duodenal bulb surface (five cases); (2) diffuse BGH manifested by a myriad of small and uniform mucosal elevations (six cases); (3) multifocal BGH producing large and well-demarcated polygonal masses (six cases); (4) BGH with concomitant acute and/ or chronic duodenitis showing marked thickening and nodularity of duodenal folds (four cases); or (5) BGH with predominant erosive duodenitis, leading to ulcerations (five cases). These radiographic findings showed a good correlation with the endoscopic and histopathologic manifestations of BGH and the frequently coexistent duodenitis.

Original languageEnglish (US)
Pages (from-to)104-108
Number of pages5
JournalGastrointestinal Radiology
Issue number1
StatePublished - Dec 1 1991


  • Brunner gland hyperplasia, diagnosis
  • Duodenum, mucosal pattern
  • Gastrointestinal tract, radiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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