Hyperosmolar urea for elective midtrimester abortion. Experience in 1,913 cases

R. T. Burkman, M. F. Atienza, T. M. King, J. A. Tonascia, J. C. Pang, A. J. Whitmore

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Intra-amniotic hyperosmolar urea (59.7 per cent) augmented by intravenous oxytocin (332 mμ per minute), prostaglandin F(2α)(20 mg.), prostaglandin F(2α)(10 mg.), or prostaglandin F(2α)(5 mg.) was utilized for 1,913 patients requesting elective midtrimester abortion. Injection-abortion intervals ranging from 13.70 to 21.49 hours were achieved with failure rates of 0.7 to 6.7 per cent. Despite frequent pre-existing medical conditions, the complication rate compared favorably with those of other methods for terminating midtrimester pregnancy such as saline amnioinfusion or dilatation and evacuation.

Original languageEnglish (US)
Pages (from-to)10-17
Number of pages8
JournalUnknown Journal
Issue number1
StatePublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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