Huntington disease in Maryland: Clinical aspects of racial variation

S. E. Folstein; G. A. Chase; W. E. Wahl; A. M. McDonnell; M. F. Folstein

Huntington disease in Maryland: Clinical aspects of racial variation

S. E. Folstein, G. A. Chase, W. E. Wahl, A. M. McDonnell, M. F. Folstein

School of Medicine

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Abstract

In a Maryland survey of Huntington disease, the prevalence in blacks was unexpectedly high and equal to that in whites. Age at onset was earlier in blacks, and their clinical features, at all ages at onset, were similar to those seen in juvenile-onset Huntington disease. Blacks had more severe bradykinesia and abnormalities of eye movement and less frequent psychiatric disorder, particularly depression.

Original language	English (US)
Pages (from-to)	168-179
Number of pages	12
Journal	American journal of human genetics
Volume	41
Issue number	2
State	Published - 1987

ASJC Scopus subject areas

Genetics
Genetics(clinical)

Cite this

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title = "Huntington disease in Maryland: Clinical aspects of racial variation",

abstract = "In a Maryland survey of Huntington disease, the prevalence in blacks was unexpectedly high and equal to that in whites. Age at onset was earlier in blacks, and their clinical features, at all ages at onset, were similar to those seen in juvenile-onset Huntington disease. Blacks had more severe bradykinesia and abnormalities of eye movement and less frequent psychiatric disorder, particularly depression.",

author = "Folstein, {S. E.} and Chase, {G. A.} and Wahl, {W. E.} and McDonnell, {A. M.} and Folstein, {M. F.}",

year = "1987",

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publisher = "Cell Press",

number = "2",

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AU - Chase, G. A.

AU - Wahl, W. E.

AU - McDonnell, A. M.

AU - Folstein, M. F.

PY - 1987

Y1 - 1987

N2 - In a Maryland survey of Huntington disease, the prevalence in blacks was unexpectedly high and equal to that in whites. Age at onset was earlier in blacks, and their clinical features, at all ages at onset, were similar to those seen in juvenile-onset Huntington disease. Blacks had more severe bradykinesia and abnormalities of eye movement and less frequent psychiatric disorder, particularly depression.

AB - In a Maryland survey of Huntington disease, the prevalence in blacks was unexpectedly high and equal to that in whites. Age at onset was earlier in blacks, and their clinical features, at all ages at onset, were similar to those seen in juvenile-onset Huntington disease. Blacks had more severe bradykinesia and abnormalities of eye movement and less frequent psychiatric disorder, particularly depression.

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AN - SCOPUS:0023232953

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Huntington disease in Maryland: Clinical aspects of racial variation

Abstract

ASJC Scopus subject areas

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