Human Y-chromosome-specific reiterated DNA

Louis M. Kunkel; Kirby D. Smith; Samuel H. Boyer

doi:10.1126/science.1257744

Human Y-chromosome-specific reiterated DNA

Louis M. Kunkel
, Kirby D. Smith
, Samuel H. Boyer

Kennedy Krieger Institute

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [³H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of Y chromosomes present. The purified Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.

Original language	English (US)
Pages (from-to)	1189-1190
Number of pages	2
Journal	Science
Volume	191
Issue number	4232
DOIs	https://doi.org/10.1126/science.1257744
State	Published - Jan 1 1976

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abstract = "Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of Y chromosomes present. The purified Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.",

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N2 - Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of Y chromosomes present. The purified Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.

AB - Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of Y chromosomes present. The purified Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.

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Human Y-chromosome-specific reiterated DNA

Abstract

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