Human papillomavirus infection of the cervix. The atypical condyloma

A. Meisels, M. Roy, M. Fortier, C. Morin, M. Casas-Cordero, K. V. Shah, H. Turgeon

Research output: Contribution to journalArticlepeer-review

130 Scopus citations


We report on 162 cases of human papillomavirus (HPV) infection of the cervix seen in a two-year period in which the cell sample showed such marked atypia that errors of interpretation could easily have been made. These atypical condylomata are difficult to diagnose cytologically as well as histologically because they mimic dysplasia or carcinoma in situ and, on smears, even invasive squamous carcinoma. HPV particles associated with fibrillar material were found within nuclei of these lesions; their nature was further proved by the immunoperoxidase test. This new form of HPV infection of the cervix showed a 9.1% rate of progression to more advanced cervical lesions. The cytologic finding of atypical condylomata is an indication for colposcopy, confirmative biopsy and appropriate treatment.

Original languageEnglish (US)
Pages (from-to)7-16
Number of pages10
JournalActa cytologica
Issue number1
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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