Human papillomavirus in women with vulvar intraepithelial neoplasia III

R. W. Jones; J. S. Park; M. R. McLean; K. V. Shah

Human papillomavirus in women with vulvar intraepithelial neoplasia III

R. W. Jones, J. S. Park, M. R. McLean, K. V. Shah

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Untreated cases of vulvar intraepithelial neoplasia (VIN) III may progress to invasive vulvar carcinoma. Tissues from 29 New Zealand women with VIN III were examined for the presence of human papillomavirus (HPV) types 6, 11, 16 and 18 by in situ hybridization and polymerase chain reaction. HPV 16, the only HPV type detected in the lesions, was identified in about half the cases. HPV-positive women were younger than HPV-negative women, and their lesions displayed koilocytosis more often. In four of five cases in which there was a progression to invasive cancer, HPV 16 was detected in both the VIN III and invasive cancer tissue.

Original language	English (US)
Pages (from-to)	1124-1126
Number of pages	3
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	35
Issue number	12
State	Published - 1990

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Cite this

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title = "Human papillomavirus in women with vulvar intraepithelial neoplasia III",

abstract = "Untreated cases of vulvar intraepithelial neoplasia (VIN) III may progress to invasive vulvar carcinoma. Tissues from 29 New Zealand women with VIN III were examined for the presence of human papillomavirus (HPV) types 6, 11, 16 and 18 by in situ hybridization and polymerase chain reaction. HPV 16, the only HPV type detected in the lesions, was identified in about half the cases. HPV-positive women were younger than HPV-negative women, and their lesions displayed koilocytosis more often. In four of five cases in which there was a progression to invasive cancer, HPV 16 was detected in both the VIN III and invasive cancer tissue.",

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year = "1990",

language = "English (US)",

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T1 - Human papillomavirus in women with vulvar intraepithelial neoplasia III

AU - Jones, R. W.

AU - Park, J. S.

AU - McLean, M. R.

AU - Shah, K. V.

PY - 1990

Y1 - 1990

N2 - Untreated cases of vulvar intraepithelial neoplasia (VIN) III may progress to invasive vulvar carcinoma. Tissues from 29 New Zealand women with VIN III were examined for the presence of human papillomavirus (HPV) types 6, 11, 16 and 18 by in situ hybridization and polymerase chain reaction. HPV 16, the only HPV type detected in the lesions, was identified in about half the cases. HPV-positive women were younger than HPV-negative women, and their lesions displayed koilocytosis more often. In four of five cases in which there was a progression to invasive cancer, HPV 16 was detected in both the VIN III and invasive cancer tissue.

AB - Untreated cases of vulvar intraepithelial neoplasia (VIN) III may progress to invasive vulvar carcinoma. Tissues from 29 New Zealand women with VIN III were examined for the presence of human papillomavirus (HPV) types 6, 11, 16 and 18 by in situ hybridization and polymerase chain reaction. HPV 16, the only HPV type detected in the lesions, was identified in about half the cases. HPV-positive women were younger than HPV-negative women, and their lesions displayed koilocytosis more often. In four of five cases in which there was a progression to invasive cancer, HPV 16 was detected in both the VIN III and invasive cancer tissue.

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SN - 0024-7758

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JF - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

IS - 12

ER -

Human papillomavirus in women with vulvar intraepithelial neoplasia III

Abstract

ASJC Scopus subject areas

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