Human keratinocyte Toll-like receptors promote distinct immune responses

Lloyd S. Miller, Robert L. Modlin

Research output: Contribution to journalComment/debatepeer-review

65 Scopus citations


It has been well established that Toll-like receptors (TLRs) are expressed by keratinocytes and respond to their respective ligands to initiate immune responses. However, it appears that keratinocytes, via differential activation of TLRs, may play a key role in determining the type of subsequent cutaneous immune response generated against a particular pathogen.

Original languageEnglish (US)
Pages (from-to)262-263
Number of pages2
JournalJournal of Investigative Dermatology
Issue number2
StatePublished - Feb 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology


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