Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.

Kerry L. Dierberg; Richard E. Chaisson

doi:10.1016/j.ccm.2013.02.003

Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.

Kerry L. Dierberg, Richard E. Chaisson

School of Medicine

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.

Original language	English (US)
Pages (from-to)	217-228
Number of pages	12
Journal	Clinics in Chest Medicine
Volume	34
Issue number	2
DOIs	https://doi.org/10.1016/j.ccm.2013.02.003
State	Published - Jun 2013

Keywords

HIV-associated tuberculosis
Human immunodeficiency virus
Tuberculosis

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.ccm.2013.02.003

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title = "Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.",

abstract = "Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.",

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N2 - Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.

AB - Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.

KW - HIV-associated tuberculosis

KW - Human immunodeficiency virus

KW - Tuberculosis

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Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.

Abstract

Keywords

ASJC Scopus subject areas

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