TY - JOUR
T1 - Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.
AU - Dierberg, Kerry L.
AU - Chaisson, Richard E.
PY - 2013/6
Y1 - 2013/6
N2 - Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.
AB - Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.
KW - HIV-associated tuberculosis
KW - Human immunodeficiency virus
KW - Tuberculosis
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U2 - 10.1016/j.ccm.2013.02.003
DO - 10.1016/j.ccm.2013.02.003
M3 - Review article
C2 - 23702172
AN - SCOPUS:84878137436
SN - 0272-5231
VL - 34
SP - 217
EP - 228
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
IS - 2
ER -