Human Cytomegalovirus: Molecular Biology

W. Gibson

doi:10.1016/B978-012374410-4.00376-9

Human Cytomegalovirus: Molecular Biology

W. Gibson

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Human cytomegalovirus has the largest genome among known human viruses and is an important, if complex, clinical entity. From a literature that is large and rapidly expanding, this article gives an overview of the molecular biology of the virus and highlights several key aspects. These include the features of transcription, translation, and DNA replication, the characteristics of major protein players in the infectious cycle, and the composition of the virus particle.

Original language	English (US)
Title of host publication	Encyclopedia of Virology
Publisher	Elsevier Ltd
Pages	485-490
Number of pages	6
ISBN (Print)	9780123744104
DOIs	https://doi.org/10.1016/B978-012374410-4.00376-9
State	Published - Jan 1 2008

Keywords

Capsid
DNA replication
Genome
Glycoproteins
Herpesvirus
Human cytomegalovirus
Tegument
Transcription
Virion

ASJC Scopus subject areas

General Immunology and Microbiology

Access to Document

10.1016/B978-012374410-4.00376-9

Cite this

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AB - Human cytomegalovirus has the largest genome among known human viruses and is an important, if complex, clinical entity. From a literature that is large and rapidly expanding, this article gives an overview of the molecular biology of the virus and highlights several key aspects. These include the features of transcription, translation, and DNA replication, the characteristics of major protein players in the infectious cycle, and the composition of the virus particle.

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KW - DNA replication

KW - Genome

KW - Glycoproteins

KW - Herpesvirus

KW - Human cytomegalovirus

KW - Tegument

KW - Transcription

KW - Virion

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EP - 490

BT - Encyclopedia of Virology

PB - Elsevier Ltd

ER -

Human Cytomegalovirus: Molecular Biology

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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