Wie soll ich messen? Operationalisierung von patienten-orientierten zielgrößen in klinischen studien

Translated title of the contribution: How to measure patient-important outcomes in clinical studies

R. Klaghofer, Milo A. Puhan

Research output: Contribution to journalArticlepeer-review


Investigators often want to assess patient-important outcomes in clinical studies. They are confronted with the challenging selection of the most appropriate instrument. Instruments should offer an unambiguous and reliable measurement. In addition, there should be evidence from validation studies that they really measure what they intend to measure. Fully standardised questionnaires often fulfil these requirements best and they are amenable to statistical analyses. However, it should be ensured that these measurement properties have been verified for the language, in which the questionnaire will be used. There are databases that inform investigators about instruments that have been validated in the respective language.

Translated title of the contributionHow to measure patient-important outcomes in clinical studies
Original languageGerman
Pages (from-to)673-677
Number of pages5
JournalTherapeutische Umschau
Issue number12
StatePublished - Dec 2007
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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