How to draw the line in biomedical research

Lisa Huang; Amir Rattner; Han Liu; Jeremy Nathans

doi:10.7554/eLife.00638

How to draw the line in biomedical research

Lisa Huang, Amir Rattner, Han Liu, Jeremy Nathans

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.

Original language	English (US)
Article number	e00638
Journal	eLife
Volume	2013
Issue number	2
DOIs	https://doi.org/10.7554/eLife.00638
State	Published - Mar 19 2013

ASJC Scopus subject areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

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10.7554/eLife.00638

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abstract = "The use of the least squares method to calculate the best-fitting line through a two-dimensional scatter plot typically requires the user to assume that one of the variables depends on the other. However, in many cases the relationship between the two variables is more complex, and it is not valid to say that one variable is independent and the other is dependent. When analysing such data researchers should consider plotting the three regression lines that can be calculated for any two-dimensional scatter plot.",

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How to draw the line in biomedical research

Abstract

ASJC Scopus subject areas

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