TY - JOUR
T1 - Hoarding in obsessive-compulsive disorder
T2 - Results from the OCD Collaborative Genetics Study
AU - Samuels, Jack F.
AU - Bienvenu, O. Joseph
AU - Pinto, Anthony
AU - Fyer, Abby J.
AU - McCracken, James T.
AU - Rauch, Scott L.
AU - Murphy, Dennis L.
AU - Grados, Marco A.
AU - Greenberg, Benjamin D.
AU - Knowles, James A.
AU - Piacentini, John
AU - Cannistraro, Paul A.
AU - Cullen, Bernadette
AU - Riddle, Mark A.
AU - Rasmussen, Steven A.
AU - Pauls, David L.
AU - Willour, Virginia L.
AU - Shugart, Yin Y.
AU - Liang, Kung-Yee
AU - Hoehn-Saric, Rudolf
AU - Nestadt, Gerald
N1 - Funding Information:
This research was supported by the National Institute of Health grant numbers R01 MH50214, K23-MH64543, and NIH/NCRR/OPD-GCRC RR00052. The authors thank the many families participating in the study; the Obsessive Compulsive Foundation; David Houseman, MD; Kathleen Merikangas, PhD; Ann Pulver, PhD; and Alec Wilson, PhD, for consultation; and clinicians and coordinators at each site: Providence (Maria Mancebo, PhD; Richard Marsland, RN; Shirley Yen, PhD); New York (Renee Goodwin, PhD; Joshua Lipsitz, PhD; Jessica Page, PsyD); Baltimore (Laura Eisen, BS; Karan Lamb, PsyD; Tracey Lichner, PhD; Yung-mei Leong, PhD; Krista Vermillion, BA; Ying Wang, MS); Boston (Dan Geller, MD; Anne Chosak, PhD; Michelle Wedig, BS; Evelyn Stewart, MD; Michael Jenike, MD; Beth Gershuny, PhD; Sabine Wilhelm, PhD); Bethesda (Lucy Justement, Diane Kazuba, V. Holland LaSalle-Ricci, Theresa B. DeGuzman); Los Angeles (R. Lindsey Bergman, PhD; Susanna Chang, PhD; Audra Langley, PhD; Amanda Pearlman, BA).
PY - 2007/4
Y1 - 2007/4
N2 - Hoarding behavior occurs frequently in obsessive-compulsive disorder (OCD). Results from previous studies suggest that individuals with OCD who have hoarding symptoms are clinically different than non-hoarders and may represent a distinct clinical group. In the present study, we compared 235 hoarding to 389 non-hoarding participants, all of whom had OCD, collected in the course of the OCD Collaborative Genetics Study. We found that, compared to non-hoarding individuals, hoarders were more likely to have symmetry obsessions and repeating, counting, and ordering compulsions; poorer insight; more severe illness; difficulty initiating or completing tasks; and indecision. Hoarders had a greater prevalence of social phobia and generalized anxiety disorder. Hoarders also had a greater prevalence of obsessive-compulsive and dependent personality disorders. Five personality traits were independently associated with hoarding: miserliness, preoccupation with details, difficulty making decisions, odd behavior or appearance, and magical thinking. Hoarding and indecision were more prevalent in the relatives of hoarding than of non-hoarding probands. Hoarding in relatives was associated with indecision in probands, independently of proband hoarding status. The findings suggest that hoarding behavior may help differentiate a distinct clinical subgroup of people with OCD and may aggregate in some OCD families. Indecision may be a risk factor for hoarding in these families.
AB - Hoarding behavior occurs frequently in obsessive-compulsive disorder (OCD). Results from previous studies suggest that individuals with OCD who have hoarding symptoms are clinically different than non-hoarders and may represent a distinct clinical group. In the present study, we compared 235 hoarding to 389 non-hoarding participants, all of whom had OCD, collected in the course of the OCD Collaborative Genetics Study. We found that, compared to non-hoarding individuals, hoarders were more likely to have symmetry obsessions and repeating, counting, and ordering compulsions; poorer insight; more severe illness; difficulty initiating or completing tasks; and indecision. Hoarders had a greater prevalence of social phobia and generalized anxiety disorder. Hoarders also had a greater prevalence of obsessive-compulsive and dependent personality disorders. Five personality traits were independently associated with hoarding: miserliness, preoccupation with details, difficulty making decisions, odd behavior or appearance, and magical thinking. Hoarding and indecision were more prevalent in the relatives of hoarding than of non-hoarding probands. Hoarding in relatives was associated with indecision in probands, independently of proband hoarding status. The findings suggest that hoarding behavior may help differentiate a distinct clinical subgroup of people with OCD and may aggregate in some OCD families. Indecision may be a risk factor for hoarding in these families.
KW - Comorbidity
KW - Hoarding
KW - Obsessive-compulsive disorder
KW - Personality
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U2 - 10.1016/j.brat.2006.05.008
DO - 10.1016/j.brat.2006.05.008
M3 - Article
C2 - 16824483
AN - SCOPUS:33847134816
SN - 0005-7967
VL - 45
SP - 673
EP - 686
JO - Behaviour Research and Therapy
JF - Behaviour Research and Therapy
IS - 4
ER -