HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients

Michelle Estrella; Derek M. Fine; Joel E. Gallant; M. Hafizur Rahman; Nagapradeep Nagajothi; Lorraine C. Racusen; Paul J. Scheel; Mohamed G. Atta

doi:10.1086/505497

HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients

Michelle Estrella, Derek M. Fine, Joel E. Gallant, M. Hafizur Rahman, Nagapradeep Nagajothi, Lorraine C. Racusen, Paul J. Scheel, Mohamed G. Atta

School of Medicine

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.

Original language	English (US)
Pages (from-to)	377-380
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	43
Issue number	3
DOIs	https://doi.org/10.1086/505497
State	Published - Aug 1 2006

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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title = "HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients",

abstract = "To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.",

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AU - Nagajothi, Nagapradeep

AU - Racusen, Lorraine C.

AU - Scheel, Paul J.

AU - Atta, Mohamed G.

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AB - To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.

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HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients

Abstract

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