HIV incidence among women of reproductive age in Malawi and Zimbabwe

Newton Kumwenda, Irving Hoffman, Mike Chirenje, Clifton Kelly, Anne Coletti, Aleen Ristow, Francis Martinson, Joelle Brown, David Chilongozi, Barbra Richardson, Zeda Rosenberg, Nancy Padian, Taha Taha

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


OBJECTIVE: The objective of this study was to determine the incidence of HIV-1. GOAL: The goal of this study was to inform HIV prevention and vaccine trials by conducting a multisite study in Malawi and Zimbabwe. STUDY DESIGN: Women of reproductive age were enrolled in a prospective study. They received 5 intensive HIV counseling and condom promotion sessions over 2 months. Subsequently, HIV-negative women completed quarterly follow-up visits. HIV incidence rates and predictors of HIV acquisition were assessed. RESULTS: A total of 2016 HIV-negative women were enrolled in the condom promotion and counseling phase of the study. Of these, 1679 were tested for HIV during follow up and 113 women seroconverted, resulting in an overall HIV incidence rate of 4.7 per 100 women-years (95% confidence interval = 3.8-5.6). Incidence rates were similar across sites. The major predictors of HIV acquisition were young age, presence of sexually transmitted infections, being unmarried, and higher educational level. CONCLUSION: The incidence of HIV continues to be high among women in both Malawi and Zimbabwe despite counseling and condom promotion.

Original languageEnglish (US)
Pages (from-to)646-651
Number of pages6
JournalSexually transmitted diseases
Issue number11
StatePublished - Nov 2006

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases


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