HIV-1 Envelope Under Attack

Wei Wei; Xiao Fang Yu

doi:10.1016/j.tim.2016.01.004

HIV-1 Envelope Under Attack

Wei Wei, Xiao Fang Yu

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

The human immunodeficiency virus type 1 (HIV-1) envelope (Env) plays a critical role in viral replication and represents a potential target for host antiviral factors. Recent work by Tada and colleagues identifies membrane-associated-RING-CH8 (MARCH8) as a potent anti-HIV factor blocking virion incorporation of Env. Thus, MARCH8 joins a growing list of host factors attacking HIV-1 Env.

Original language	English (US)
Pages (from-to)	164-166
Number of pages	3
Journal	Trends in Microbiology
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.tim.2016.01.004
State	Published - Mar 1 2016

Keywords

Envelope glycoprotein
HIV-1
MARCH8
Virion incorporation

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

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10.1016/j.tim.2016.01.004

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title = "HIV-1 Envelope Under Attack",

abstract = "The human immunodeficiency virus type 1 (HIV-1) envelope (Env) plays a critical role in viral replication and represents a potential target for host antiviral factors. Recent work by Tada and colleagues identifies membrane-associated-RING-CH8 (MARCH8) as a potent anti-HIV factor blocking virion incorporation of Env. Thus, MARCH8 joins a growing list of host factors attacking HIV-1 Env.",

keywords = "Envelope glycoprotein, HIV-1, MARCH8, Virion incorporation",

author = "Wei Wei and Yu, {Xiao Fang}",

note = "Funding Information: This work is supported by funding from the Chinese Ministry of Science and Technology (number 2012CB911100 and number 2013ZX0001-005) and the Chinese Ministry of Education (number IRT1016), the Key Laboratory of Molecular Virology, Jilin Province (20102209). Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd.",

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T1 - HIV-1 Envelope Under Attack

AU - Wei, Wei

AU - Yu, Xiao Fang

N1 - Funding Information: This work is supported by funding from the Chinese Ministry of Science and Technology (number 2012CB911100 and number 2013ZX0001-005) and the Chinese Ministry of Education (number IRT1016), the Key Laboratory of Molecular Virology, Jilin Province (20102209). Publisher Copyright: © 2016 Elsevier Ltd.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - The human immunodeficiency virus type 1 (HIV-1) envelope (Env) plays a critical role in viral replication and represents a potential target for host antiviral factors. Recent work by Tada and colleagues identifies membrane-associated-RING-CH8 (MARCH8) as a potent anti-HIV factor blocking virion incorporation of Env. Thus, MARCH8 joins a growing list of host factors attacking HIV-1 Env.

AB - The human immunodeficiency virus type 1 (HIV-1) envelope (Env) plays a critical role in viral replication and represents a potential target for host antiviral factors. Recent work by Tada and colleagues identifies membrane-associated-RING-CH8 (MARCH8) as a potent anti-HIV factor blocking virion incorporation of Env. Thus, MARCH8 joins a growing list of host factors attacking HIV-1 Env.

KW - Envelope glycoprotein

KW - HIV-1

KW - MARCH8

KW - Virion incorporation

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SP - 164

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JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 3

ER -

HIV-1 Envelope Under Attack

Abstract

Keywords

ASJC Scopus subject areas

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