Histomorphometry of hydroxyapatite coated and uncoated porous titanium bone implants

A. Moroni; V. L. Caja; E. L. Egger; L. Trinchese; E. Y.S. Chao

doi:10.1016/0142-9612(94)90119-8

Histomorphometry of hydroxyapatite coated and uncoated porous titanium bone implants

A. Moroni, V. L. Caja, E. L. Egger, L. Trinchese, E. Y.S. Chao

Research output: Contribution to journal › Article › peer-review

Abstract

Two different groups of hydroxyapatite (HA) coated and uncoated porous titanium implants, 250-350 μm and 500-700 μm diameter beads, were press-fitted into femoral canine cancellous bone. After 12wks, the dogs were killed and histomorphometric backscattered electron microscopy studies were carried out. Comparing HA coated versus uncoated implants in the 250-350 μm bead diameter group, the percentage of bone (P = 0.01) and bone index (P = 0.01) were higher in the HA coated implants. Comparing HA coated versus uncoated implants in the 500-700 μm bead diameter group, bone ingrowth (P = 0.01) and bone depth penetration (P = 0.008) were higher in HA coated samples. It can be concluded that the HA coating was an effective method for improving bone formation and ingrowth in the porous implants.

Original language	English (US)
Pages (from-to)	926-930
Number of pages	5
Journal	Biomaterials
Volume	15
Issue number	11
DOIs	https://doi.org/10.1016/0142-9612(94)90119-8
State	Published - Sep 1994
Externally published	Yes

Keywords

Bone ingrowth
hydroxyapatite coating
porous coating
titanium

ASJC Scopus subject areas

Mechanics of Materials
Ceramics and Composites
Bioengineering
Biophysics
Biomaterials

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10.1016/0142-9612(94)90119-8

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title = "Histomorphometry of hydroxyapatite coated and uncoated porous titanium bone implants",

abstract = "Two different groups of hydroxyapatite (HA) coated and uncoated porous titanium implants, 250-350 μm and 500-700 μm diameter beads, were press-fitted into femoral canine cancellous bone. After 12wks, the dogs were killed and histomorphometric backscattered electron microscopy studies were carried out. Comparing HA coated versus uncoated implants in the 250-350 μm bead diameter group, the percentage of bone (P = 0.01) and bone index (P = 0.01) were higher in the HA coated implants. Comparing HA coated versus uncoated implants in the 500-700 μm bead diameter group, bone ingrowth (P = 0.01) and bone depth penetration (P = 0.008) were higher in HA coated samples. It can be concluded that the HA coating was an effective method for improving bone formation and ingrowth in the porous implants.",

keywords = "Bone ingrowth, hydroxyapatite coating, porous coating, titanium",

author = "A. Moroni and Caja, {V. L.} and Egger, {E. L.} and L. Trinchese and Chao, {E. Y.S.}",

note = "Funding Information: The authors would like to thank Fred Schultz for designing the instruments used for implant insertion, and specimen cutting, and {\textquoteleft}Area di Ricerca Corrente 5{\textquoteright} of the Rizzoli Institute and the Mayo Foundation for funding the research.",

year = "1994",

month = sep,

doi = "10.1016/0142-9612(94)90119-8",

language = "English (US)",

volume = "15",

pages = "926--930",

journal = "Biomaterials",

issn = "0142-9612",

publisher = "Elsevier Ltd",

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T1 - Histomorphometry of hydroxyapatite coated and uncoated porous titanium bone implants

AU - Moroni, A.

AU - Caja, V. L.

AU - Egger, E. L.

AU - Trinchese, L.

AU - Chao, E. Y.S.

N1 - Funding Information: The authors would like to thank Fred Schultz for designing the instruments used for implant insertion, and specimen cutting, and ‘Area di Ricerca Corrente 5’ of the Rizzoli Institute and the Mayo Foundation for funding the research.

PY - 1994/9

Y1 - 1994/9

N2 - Two different groups of hydroxyapatite (HA) coated and uncoated porous titanium implants, 250-350 μm and 500-700 μm diameter beads, were press-fitted into femoral canine cancellous bone. After 12wks, the dogs were killed and histomorphometric backscattered electron microscopy studies were carried out. Comparing HA coated versus uncoated implants in the 250-350 μm bead diameter group, the percentage of bone (P = 0.01) and bone index (P = 0.01) were higher in the HA coated implants. Comparing HA coated versus uncoated implants in the 500-700 μm bead diameter group, bone ingrowth (P = 0.01) and bone depth penetration (P = 0.008) were higher in HA coated samples. It can be concluded that the HA coating was an effective method for improving bone formation and ingrowth in the porous implants.

AB - Two different groups of hydroxyapatite (HA) coated and uncoated porous titanium implants, 250-350 μm and 500-700 μm diameter beads, were press-fitted into femoral canine cancellous bone. After 12wks, the dogs were killed and histomorphometric backscattered electron microscopy studies were carried out. Comparing HA coated versus uncoated implants in the 250-350 μm bead diameter group, the percentage of bone (P = 0.01) and bone index (P = 0.01) were higher in the HA coated implants. Comparing HA coated versus uncoated implants in the 500-700 μm bead diameter group, bone ingrowth (P = 0.01) and bone depth penetration (P = 0.008) were higher in HA coated samples. It can be concluded that the HA coating was an effective method for improving bone formation and ingrowth in the porous implants.

KW - Bone ingrowth

KW - hydroxyapatite coating

KW - porous coating

KW - titanium

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AN - SCOPUS:0028501325

SN - 0142-9612

VL - 15

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EP - 930

JO - Biomaterials

JF - Biomaterials

IS - 11

ER -

Histomorphometry of hydroxyapatite coated and uncoated porous titanium bone implants

Abstract

Keywords

ASJC Scopus subject areas

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