Histologic characterization of primary ciliary dyskinesia chronic rhinosinusitis

Sulgi Kim; Lang Li; Feng Chang Lin; Taylor Stack; Meredith M. Lamb; Ibtisam Mohammad; Meghan Norris; Cristine Klatt-Cromwell; Brian D. Thorp; Charles S. Ebert; Daniel Masters; Brent A. Senior; Frederic B. Askin; Adam J. Kimple

doi:10.1002/alr.23303

Histologic characterization of primary ciliary dyskinesia chronic rhinosinusitis

Sulgi Kim, Lang Li, Feng Chang Lin, Taylor Stack, Meredith M. Lamb, Ibtisam Mohammad, Meghan Norris, Cristine Klatt-Cromwell, Brian D. Thorp, Charles S. Ebert, Daniel Masters, Brent A. Senior, Frederic B. Askin, Adam J. Kimple

Research output: Contribution to journal › Article › peer-review

Abstract

Key points: We present the largest cohort of structured histopathology reports on primary ciliary dyskinesia-related chronic rhinosinusitis (PCD-CRS). Despite endoscopic differences, PCD-CRS and cystic fibrosis-related chronic rhinosinusitis (CF-CRS) had similar structured histopathology reports. Compared to healthy patients and those with idiopathic chronic rhinosinusitis without nasal polyps, patients with PCD-CRS had an increased neutrophil count.

Original language	English (US)
Pages (from-to)	990-994
Number of pages	5
Journal	International Forum of Allergy and Rhinology
Volume	14
Issue number	5
DOIs	https://doi.org/10.1002/alr.23303
State	Published - May 2024
Externally published	Yes

Keywords

chronic rhinosinusitis
ciliary motility
hereditary
musocilliary clearance

ASJC Scopus subject areas

Immunology and Allergy
Otorhinolaryngology

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10.1002/alr.23303

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Kim, S., Li, L., Lin, F. C., Stack, T., Lamb, M. M., Mohammad, I., Norris, M., Klatt-Cromwell, C., Thorp, B. D., Ebert, C. S., Masters, D., Senior, B. A., Askin, F. B., & Kimple, A. J. (2024). Histologic characterization of primary ciliary dyskinesia chronic rhinosinusitis. International Forum of Allergy and Rhinology, 14(5), 990-994. https://doi.org/10.1002/alr.23303

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abstract = "Key points: We present the largest cohort of structured histopathology reports on primary ciliary dyskinesia-related chronic rhinosinusitis (PCD-CRS). Despite endoscopic differences, PCD-CRS and cystic fibrosis-related chronic rhinosinusitis (CF-CRS) had similar structured histopathology reports. Compared to healthy patients and those with idiopathic chronic rhinosinusitis without nasal polyps, patients with PCD-CRS had an increased neutrophil count.",

keywords = "chronic rhinosinusitis, ciliary motility, hereditary, musocilliary clearance",

author = "Sulgi Kim and Lang Li and Lin, {Feng Chang} and Taylor Stack and Lamb, {Meredith M.} and Ibtisam Mohammad and Meghan Norris and Cristine Klatt-Cromwell and Thorp, {Brian D.} and Ebert, {Charles S.} and Daniel Masters and Senior, {Brent A.} and Askin, {Frederic B.} and Kimple, {Adam J.}",

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year = "2024",

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doi = "10.1002/alr.23303",

language = "English (US)",

volume = "14",

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AU - Kim, Sulgi

AU - Li, Lang

AU - Lin, Feng Chang

AU - Stack, Taylor

AU - Lamb, Meredith M.

AU - Mohammad, Ibtisam

AU - Norris, Meghan

AU - Klatt-Cromwell, Cristine

AU - Thorp, Brian D.

AU - Ebert, Charles S.

AU - Masters, Daniel

AU - Senior, Brent A.

AU - Askin, Frederic B.

AU - Kimple, Adam J.

PY - 2024/5

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AB - Key points: We present the largest cohort of structured histopathology reports on primary ciliary dyskinesia-related chronic rhinosinusitis (PCD-CRS). Despite endoscopic differences, PCD-CRS and cystic fibrosis-related chronic rhinosinusitis (CF-CRS) had similar structured histopathology reports. Compared to healthy patients and those with idiopathic chronic rhinosinusitis without nasal polyps, patients with PCD-CRS had an increased neutrophil count.

KW - chronic rhinosinusitis

KW - ciliary motility

KW - hereditary

KW - musocilliary clearance

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Histologic characterization of primary ciliary dyskinesia chronic rhinosinusitis

Abstract

Keywords

ASJC Scopus subject areas

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