There is increasing evidence that human basophils accumulate at sites of chronic inflammation,and, in particular, in allergic asthma. Investigators have, therefore, become very interested in identifying proteins that activate these cells. Recently, the gene encoding a candidate for this function, a novel molecule, the IgE-dependent histamine-releasing factor, was cloned.
|Original language||English (US)|
|Number of pages||6|
|Journal||Current Opinion in Immunology|
|State||Published - Dec 1996|
ASJC Scopus subject areas
- Immunology and Allergy