@inproceedings{487397aa0f0e4aeda1052d0df73b5a2f,
title = "Higher dimensional fMRI connectivity dynamics show reduced dynamism in schizophrenia patients",
abstract = "Assessments of functional connectivity between brain networks is a fixture of resting state fMRI research. Until very recently most of this work proceeded from an assumption of stationarity in resting state network connectivity. In the last few years however, interest in moving beyond this simplifying assumption has grown considerably. Applying group temporal independent component analysis (tICA) to a set of time-varying functional network connectivity (FNC) matrices derived from a large multi-site fMRI dataset (N=314; 163 healthy, 151 schizophrenia patients), we obtain a set of five basic correlation patterns (component spatial maps (SMs)) from which observed FNCs can be expressed as mutually independent linear combinations, ie. the coefficient on each SM in the linear combination is statistically independent of the others. We study dynamic properties of network connectivity as they are reflected in this five-dimensional space, and report stark differences in connectivity dynamics between schizophrenia patients and healthy controls",
keywords = "dynamics, fMRI, independent component analysis, network connectivity, schizophrenia",
author = "Miller, {Robyn L.} and Maziar Yaesoubi and Calhoun, {Vince D.} and Shruti Gopal",
year = "2014",
month = jan,
day = "1",
doi = "10.1109/PRNI.2014.6858534",
language = "English (US)",
isbn = "9781479941506",
series = "Proceedings - 2014 International Workshop on Pattern Recognition in Neuroimaging, PRNI 2014",
publisher = "IEEE Computer Society",
booktitle = "Proceedings - 2014 International Workshop on Pattern Recognition in Neuroimaging, PRNI 2014",
note = "4th International Workshop on Pattern Recognition in Neuroimaging, PRNI 2014 ; Conference date: 04-06-2014 Through 06-06-2014",
}