High-Risk, High-Reward Genetics in ASD

Christina A. Castellani, Dan E. Arking

Research output: Contribution to journalComment/debatepeer-review

2 Scopus citations


In a recent issue of Cell, Satterstrom et al. leverage de novo high-impact variants to identify 102 genes associated with autism spectrum disorder (ASD). Most of these genes have roles in regulation of gene expression or neuronal communication, implicating both developmental and functional changes in ASD.

Original languageEnglish (US)
Pages (from-to)407-410
Number of pages4
Issue number3
StatePublished - Feb 5 2020

ASJC Scopus subject areas

  • General Neuroscience


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