High-resolution methods for the measurement of scalar coupling constants

Yanqin Lin; Qing Zeng; Liangjie Lin; Zhong Chen; Peter B. Barker

doi:10.1016/j.pnmrs.2018.08.003

High-resolution methods for the measurement of scalar coupling constants

Yanqin Lin, Qing Zeng, Liangjie Lin, Zhong Chen, Peter B. Barker

School of Medicine

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Scalar couplings provide important information regarding molecular structure and dynamics. The measurement of scalar coupling constants constitutes a topic of interest and significance in NMR spectroscopy. However, the measurement of J values is often not straightforward because of complex signal splitting patterns and signal overlap. Many methods have been proposed for the measurement of scalar coupling constants, both for homonuclear and heteronuclear cases. Different approaches to the measurement of scalar coupling constants are reviewed here with several applications presented. The accurate measurement of scalar coupling constants can greatly facilitate molecular structure elucidation and the study of molecule dynamics.

Original language	English (US)
Pages (from-to)	135-159
Number of pages	25
Journal	Progress in Nuclear Magnetic Resonance Spectroscopy
Volume	109
DOIs	https://doi.org/10.1016/j.pnmrs.2018.08.003
State	Published - Dec 2018

Keywords

Homonuclear/heteronuclear scalar coupling
J-upscaling
Nuclear magnetic resonance (NMR)
Phase-sensitive J-spectroscopy
Selective measurement
Spin-state-selective

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Nuclear and High Energy Physics
Spectroscopy

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10.1016/j.pnmrs.2018.08.003

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title = "High-resolution methods for the measurement of scalar coupling constants",

abstract = "Scalar couplings provide important information regarding molecular structure and dynamics. The measurement of scalar coupling constants constitutes a topic of interest and significance in NMR spectroscopy. However, the measurement of J values is often not straightforward because of complex signal splitting patterns and signal overlap. Many methods have been proposed for the measurement of scalar coupling constants, both for homonuclear and heteronuclear cases. Different approaches to the measurement of scalar coupling constants are reviewed here with several applications presented. The accurate measurement of scalar coupling constants can greatly facilitate molecular structure elucidation and the study of molecule dynamics.",

keywords = "Homonuclear/heteronuclear scalar coupling, J-upscaling, Nuclear magnetic resonance (NMR), Phase-sensitive J-spectroscopy, Selective measurement, Spin-state-selective",

author = "Yanqin Lin and Qing Zeng and Liangjie Lin and Zhong Chen and Barker, {Peter B.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier B.V.",

year = "2018",

month = dec,

doi = "10.1016/j.pnmrs.2018.08.003",

language = "English (US)",

volume = "109",

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journal = "Progress in Nuclear Magnetic Resonance Spectroscopy",

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TY - JOUR

T1 - High-resolution methods for the measurement of scalar coupling constants

AU - Lin, Yanqin

AU - Zeng, Qing

AU - Lin, Liangjie

AU - Chen, Zhong

AU - Barker, Peter B.

PY - 2018/12

Y1 - 2018/12

N2 - Scalar couplings provide important information regarding molecular structure and dynamics. The measurement of scalar coupling constants constitutes a topic of interest and significance in NMR spectroscopy. However, the measurement of J values is often not straightforward because of complex signal splitting patterns and signal overlap. Many methods have been proposed for the measurement of scalar coupling constants, both for homonuclear and heteronuclear cases. Different approaches to the measurement of scalar coupling constants are reviewed here with several applications presented. The accurate measurement of scalar coupling constants can greatly facilitate molecular structure elucidation and the study of molecule dynamics.

AB - Scalar couplings provide important information regarding molecular structure and dynamics. The measurement of scalar coupling constants constitutes a topic of interest and significance in NMR spectroscopy. However, the measurement of J values is often not straightforward because of complex signal splitting patterns and signal overlap. Many methods have been proposed for the measurement of scalar coupling constants, both for homonuclear and heteronuclear cases. Different approaches to the measurement of scalar coupling constants are reviewed here with several applications presented. The accurate measurement of scalar coupling constants can greatly facilitate molecular structure elucidation and the study of molecule dynamics.

KW - Homonuclear/heteronuclear scalar coupling

KW - J-upscaling

KW - Nuclear magnetic resonance (NMR)

KW - Phase-sensitive J-spectroscopy

KW - Selective measurement

KW - Spin-state-selective

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U2 - 10.1016/j.pnmrs.2018.08.003

DO - 10.1016/j.pnmrs.2018.08.003

M3 - Review article

C2 - 30527134

AN - SCOPUS:85052141048

SN - 0079-6565

VL - 109

SP - 135

EP - 159

JO - Progress in Nuclear Magnetic Resonance Spectroscopy

JF - Progress in Nuclear Magnetic Resonance Spectroscopy

ER -

High-resolution methods for the measurement of scalar coupling constants

Abstract

Keywords

ASJC Scopus subject areas

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