@inproceedings{3404b6aefa494df99cfd2d4cffecd080,
title = "High precision profiling of glycopeptides using HPLC-CHIP/MS TOF",
abstract = "Protein glycosylation is critically important to biological function and disease state. An effective method for the selective isolation of N-linked glycopeptides has been developed, based on the conjugation of glycoproteins to a solid support using hydrazine chemistry [1]. Due to extreme sample complexity, separation methods such as nano-LC/MS has been used as an analytical tool for human serum samples but we illustrate here that a microfluidic device can achieve superior performance in both sensitivity and reproducibility for profiling complex samples such as glycosylated proteins.",
author = "Kevin Killeen and Hongfeng Yin and Reid Brennen and Karen Seaward and Rudi Grimm and Li, {Xiao Jun} and Hui Zhang and Ruedi Aebersold",
year = "2005",
month = jan,
day = "1",
language = "English (US)",
isbn = "0974361119",
series = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Transducer Research Foundation",
pages = "274--276",
booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference",
note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",
}