High-degree concentration of bio-agents using electrokinetic manipulations

Kent Murray; Tza Huei Wang; Keith Rebello; James Crookston; Joseph Miragliotta

doi:10.1109/LSSA.2006.250373

High-degree concentration of bio-agents using electrokinetic manipulations

Kent Murray
, Tza Huei Wang
, Keith Rebello
, James Crookston
, Joseph Miragliotta

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Techniques used for the upstream collection of bio-warfare agents often result in a large, dilute sample volume composed of a wide variety of moieties. Nonetheless, current bioassays, though constantly being refined, benefit from a highly concentrated sample, leading to an enhanced signal to noise ratio and increasing the ultimate sensitivity. This report describes an electrokinetics-based sample concentration device designed to concentrate bio-agents, such as bacillus spores, from a relatively large volume (∼ 500 μl) to be within a nanoliter volume for downstream target processing and detection. The concentrator can later be integrated with other fluidic sample processing devices and sensors for the development of a stand-alone bio-agent surveillance system.

Original language	English (US)
Title of host publication	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
DOIs	https://doi.org/10.1109/LSSA.2006.250373
State	Published - 2006
Externally published	Yes
Event	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006 - Bethesda, MD, United States Duration: Jul 13 2006 → Jul 14 2006

Publication series

Name	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006

Other

Other	2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
Country/Territory	United States
City	Bethesda, MD
Period	7/13/06 → 7/14/06

ASJC Scopus subject areas

Health(social science)
Assessment and Diagnosis
General Medicine
Health Information Management
Electrical and Electronic Engineering
Human-Computer Interaction
Computer Science Applications
Signal Processing

Access to Document

10.1109/LSSA.2006.250373

Cite this

High-degree concentration of bio-agents using electrokinetic manipulations. / Murray, Kent; Wang, Tza Huei; Rebello, Keith et al.
2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006. 2006. 4015844 (2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Murray, K, Wang, TH, Rebello, K, Crookston, J & Miragliotta, J 2006, High-degree concentration of bio-agents using electrokinetic manipulations. in 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006., 4015844, 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006, 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006, Bethesda, MD, United States, 7/13/06. https://doi.org/10.1109/LSSA.2006.250373

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abstract = "Techniques used for the upstream collection of bio-warfare agents often result in a large, dilute sample volume composed of a wide variety of moieties. Nonetheless, current bioassays, though constantly being refined, benefit from a highly concentrated sample, leading to an enhanced signal to noise ratio and increasing the ultimate sensitivity. This report describes an electrokinetics-based sample concentration device designed to concentrate bio-agents, such as bacillus spores, from a relatively large volume (∼ 500 μl) to be within a nanoliter volume for downstream target processing and detection. The concentrator can later be integrated with other fluidic sample processing devices and sensors for the development of a stand-alone bio-agent surveillance system.",

author = "Kent Murray and Wang, \{Tza Huei\} and Keith Rebello and James Crookston and Joseph Miragliotta",

year = "2006",

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AB - Techniques used for the upstream collection of bio-warfare agents often result in a large, dilute sample volume composed of a wide variety of moieties. Nonetheless, current bioassays, though constantly being refined, benefit from a highly concentrated sample, leading to an enhanced signal to noise ratio and increasing the ultimate sensitivity. This report describes an electrokinetics-based sample concentration device designed to concentrate bio-agents, such as bacillus spores, from a relatively large volume (∼ 500 μl) to be within a nanoliter volume for downstream target processing and detection. The concentrator can later be integrated with other fluidic sample processing devices and sensors for the development of a stand-alone bio-agent surveillance system.

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T3 - 2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006

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ER -

High-degree concentration of bio-agents using electrokinetic manipulations

Abstract

Publication series

Other

ASJC Scopus subject areas

Access to Document

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