Herpes Simplex Virus Cervicitis Mimicking Preterm Premature Rupture of Membranes

Christina N. Cordeiro, Janyne Althaus, Anne Burke, Cynthia Argani

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


BACKGROUND: The diagnosis of preterm premature rupture of membranes (PROM) is based on pooling, ferning, and Nitrazine tests; definitive diagnosis is made with a blue dye test. CASE: A 21-year-old woman, gravida 1 para 0, at 25 5/7 weeks of gestation was admitted for preterm PROM with positive findings of pooling, Nitrazine, and ferning. Her cervix was bluish with white plaques. Amniotic fluid volume was normal. On hospital day 8, her discharge ceased; examination was negative for pooling, Nitrazine, and ferning. A blue dye tampon test was negative. A Pap test result from her hospitalization returned consistent with herpes infection. CONCLUSION: The diagnosis of preterm PROM should be constantly reevaluated in the setting of a normal amniotic fluid volume.

Original languageEnglish (US)
Pages (from-to)378-380
Number of pages3
JournalObstetrics and gynecology
Issue number2
StatePublished - Aug 23 2015

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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