Herpes simplex infections in the critical care setting

Research output: Contribution to journalArticlepeer-review


Infections caused by herpes simplex virus (HSV) types 1 and 2 are widely prevalent and usually asymptomatic. In the immunocompromised or severely ill patient, however, HSV can cause a variety of mucosal and systemic syndromes. Organ systems most susceptible include the gastrointestinal tract, lungs, and the central nervous system. Systemic disseminated disease may also occur. With the exception of herpes encephalitis, clinical diagnosis of serious HSV infections is difficult, because it occurs in hosts who are susceptible to a wide range of infectious and metabolic problems. We review the presenting syndromes of HSV infection in the critically ill patient, and outline current concepts for diagnosis and treatment.

Original languageEnglish (US)
Pages (from-to)93-103
Number of pages11
JournalJournal of Intensive Care Medicine
Issue number2
StatePublished - 1997

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'Herpes simplex infections in the critical care setting'. Together they form a unique fingerprint.

Cite this