Hepatorenal syndrome

Sharon Turban; Paul J. Thuluvath; Mohamed G. Atta

doi:10.3748/wjg.v13.i30.4046

Hepatorenal syndrome

Sharon Turban, Paul J. Thuluvath, Mohamed G. Atta

School of Medicine

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.

Original language	English (US)
Pages (from-to)	4046-4055
Number of pages	10
Journal	World Journal of Gastroenterology
Volume	13
Issue number	30
DOIs	https://doi.org/10.3748/wjg.v13.i30.4046
State	Published - Aug 14 2007

Keywords

Acute renal failure
Dialysis
End stage liver disease
Hepatorenal syndrome
Liver transplantation
Transjugular intrahepatic portosystemic shunts

ASJC Scopus subject areas

Gastroenterology

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10.3748/wjg.v13.i30.4046

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title = "Hepatorenal syndrome",

abstract = "Hepatorenal syndrome (HRS) is a {"}functional{"} and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.",

keywords = "Acute renal failure, Dialysis, End stage liver disease, Hepatorenal syndrome, Liver transplantation, Transjugular intrahepatic portosystemic shunts",

author = "Sharon Turban and Thuluvath, {Paul J.} and Atta, {Mohamed G.}",

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TY - JOUR

T1 - Hepatorenal syndrome

AU - Turban, Sharon

AU - Thuluvath, Paul J.

AU - Atta, Mohamed G.

PY - 2007/8/14

Y1 - 2007/8/14

N2 - Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.

AB - Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.

KW - Acute renal failure

KW - Dialysis

KW - End stage liver disease

KW - Hepatorenal syndrome

KW - Liver transplantation

KW - Transjugular intrahepatic portosystemic shunts

UR - http://www.scopus.com/inward/record.url?scp=34548218172&partnerID=8YFLogxK

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DO - 10.3748/wjg.v13.i30.4046

M3 - Review article

C2 - 17696221

AN - SCOPUS:34548218172

SN - 1007-9327

VL - 13

SP - 4046

EP - 4055

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

IS - 30

ER -

Hepatorenal syndrome

Abstract

Keywords

ASJC Scopus subject areas

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