TY - JOUR
T1 - Hepatocyte plasma membrane ecto-ATPase ( pp120 HA4) is a substrate for tyrosine kinase activity of the insulin receptor
AU - Margolis, Ronald N.
AU - Schell, Michael John
AU - Taylor, Simeon I.
AU - Hubbard, Ann L.
N1 - Funding Information:
We thank Drs. S.-H. Lin, P. Meier and F. Suchy for their antibodies. This work was supported by grants from the American Diabetes Association, Washington, DC Area Affiliate (R.N.M.), the Diabetes Research and Education Foundation (R.N.M.), and the National institutes of Health (GM 29185, A.LH.). We are afso grateful to the support received during the course of this study from the Intramural Research Program of the National institute of Diabetes, Dlgestfve, and Kidney Diseases. During the course of this work Dr. Margdls was supported while on Sabbatical leave in part by funds from the Diabetes Branch, NIDDK.
PY - 1990/1/30
Y1 - 1990/1/30
N2 - pp120 HA4, a membrane protein found in hepatocyte plasma membranes and a substrate for the insulin receptor tyrosine kinase, was purified to homogeneity, subjected to partial proteolysis, and peptides were sequenced by Edman degradation. Six amino acid sequences were obtained, and they matched the deduced amino acid sequences of six regions of a hepatocyte membrane protein called ecto-ATPase.
AB - pp120 HA4, a membrane protein found in hepatocyte plasma membranes and a substrate for the insulin receptor tyrosine kinase, was purified to homogeneity, subjected to partial proteolysis, and peptides were sequenced by Edman degradation. Six amino acid sequences were obtained, and they matched the deduced amino acid sequences of six regions of a hepatocyte membrane protein called ecto-ATPase.
UR - https://www.scopus.com/pages/publications/0025138734
UR - https://www.scopus.com/pages/publications/0025138734#tab=citedBy
U2 - 10.1016/0006-291X(90)90845-E
DO - 10.1016/0006-291X(90)90845-E
M3 - Article
C2 - 2137339
AN - SCOPUS:0025138734
SN - 0006-291X
VL - 166
SP - 562
EP - 566
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -