TY - JOUR
T1 - Hepatocellular carcinoma presenting as a precocious cutaneous metastasis
AU - Royer, Michael C.
AU - Rush, Walter L.
AU - Lupton, George P.
PY - 2008/2/1
Y1 - 2008/2/1
N2 - The authors report a case of hepatocellular carcinoma (HCC) diagnosed by evaluation of a cutaneous metastasis in a patient without a prior diagnosis of HCC. Subsequent evaluation confirmed the presence of additional widespread metastatic disease. The medical literature is reviewed with regards to cutaneous metastasis, including precocious metastasis, of HCC. The pathologic evaluation of HCC is reviewed, including a discussion of the immunohistochemical profile of this malignancy and the utility of hepatocyte paraffin 1, CD10, and polyclonal carcinoembryonic antigen (pCEA) immunohistochemical stains.
AB - The authors report a case of hepatocellular carcinoma (HCC) diagnosed by evaluation of a cutaneous metastasis in a patient without a prior diagnosis of HCC. Subsequent evaluation confirmed the presence of additional widespread metastatic disease. The medical literature is reviewed with regards to cutaneous metastasis, including precocious metastasis, of HCC. The pathologic evaluation of HCC is reviewed, including a discussion of the immunohistochemical profile of this malignancy and the utility of hepatocyte paraffin 1, CD10, and polyclonal carcinoembryonic antigen (pCEA) immunohistochemical stains.
KW - Cutaneous metastases
KW - Hepatocellular carcinoma
KW - Immunohistochemistry
UR - http://www.scopus.com/inward/record.url?scp=38549174681&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38549174681&partnerID=8YFLogxK
U2 - 10.1097/DAD.0b013e31815ea24f
DO - 10.1097/DAD.0b013e31815ea24f
M3 - Article
C2 - 18212552
AN - SCOPUS:38549174681
SN - 0193-1091
VL - 30
SP - 77
EP - 80
JO - American Journal of Dermatopathology
JF - American Journal of Dermatopathology
IS - 1
ER -