Hepatoblastoma and familial adenomatous polyposis

J. E. Garber, F. P. Li, J. E. Kingston, A. J. Krush, L. C. Strong, M. J. Finegold, L. Bertario, S. Bülow, A. Filippone, T. Gedde-dahl, H. J. Järvinen

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Eleven children have been identified as having hepatoblastoma and a family history of adenomatous polyposis, and 14 additional instances of this association have been collected from the literature. Among the 11 survivors of hepatoblastoma in the combined series, adenomatous lesions have been sought in seven and detected in six patients at ages 7 to 25 years. Five of these patients also have congenital hypertrophy of the rential pigment epithelium, a marker for carriers of the polyposis gene. These findings strengthen the association between hepatoblastoma and familial adenomatous polyposis and have led to the establishment of the Hepatoblastoma-Adenomatous Polyposis Registry.

Original languageEnglish (US)
Pages (from-to)1626-1628
Number of pages3
JournalJournal of the National Cancer Institute
Issue number20
StatePublished - Dec 21 1988

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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