Hepatobiliary cancers clinical practice guidelines in oncology

Al B. Benson, Tanios Bekaii-Saab, Edgar Ben-Josef, Leslie Blumgart, Bryan M. Clary, Steven A. Curley, Rene Davila, Craig C. Earle, William D. Ensminger, John F. Gibbs, Daniel Laheru, Alan N. Langnas, Sean J. Mulvihill, Albert A. Nemcek, James A. Posey, Elin R. Sigurdson, Mika Sinanan, Jean Nicolas Vauthey, Alan P. Venook, Lawrence D. WagmanTimothy J. Yeatman

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Hepatobiliary cancers are common worldwide and highly lethal. Hepatocellular carcinoma is the most common hepatobiliary malignancy and the seventh most common cancer worldwide. Gallbladder cancer is the most common biliary tract malignancy, accounting for approximately 5000 newly diagnosed cases in the United States. Cholangiocarcinomas are diagnosed throughout the biliary tree and are usually classified as intrahepatic or extrahepatic. Intrahepatic cholangiocarcinomas arise from intrahepatic small-duct radicals, whereas extrahepatic cholangiocarcinomas encompass hilar carcinomas (including Klatskin's tumors). These guidelines discuss these subtypes of hepatobiliary cancer and the epidemiology, pathology, etiology, staging, diagnosis, and treatment of each subtype.

Original languageEnglish (US)
Pages (from-to)728-750
Number of pages23
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number8
StatePublished - Sep 2006


  • Chemoembolization
  • Cholangiocarcinomas
  • Cirrhosis
  • Gallbladder cancer
  • Hepatitis C
  • Hepatocellular carcinoma
  • NCCN Clinical Practice Guidelines
  • Surgical resection
  • Transplantation
  • Tumor ablation

ASJC Scopus subject areas

  • Oncology


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