TY - JOUR
T1 - Hepatitis C in HIV-infected individuals
T2 - Cure and control, right now
AU - Thomas, David L.
AU - Leoutsakas, Dennis
AU - Zabransky, Tomas
AU - Kumar, M. Suresh
PY - 2011
Y1 - 2011
N2 - For persons living with HIV, hepatitis C is a major public health problem that must be controlled and could be eliminated. The challenge arises because the hepatitis C virus (HCV) is prevalent among HIV-infected persons in most parts of the world, because HIV worsens all HCV outcomes, and because HCV may add additional individual economic and psychosocial complications to HIV disease. Despite the major benefits of antiretroviral therapy on HIV outcomes, antiretroviral therapy is not sufficient to halt the complications of HCV. Nonetheless, HCV can be controlled at all stages, including prevention of infection and cure. Thus, HCV is an eradicable disease. There are significant inequalities worldwide in HCV control that could markedly constrain the impact of these measures.
AB - For persons living with HIV, hepatitis C is a major public health problem that must be controlled and could be eliminated. The challenge arises because the hepatitis C virus (HCV) is prevalent among HIV-infected persons in most parts of the world, because HIV worsens all HCV outcomes, and because HCV may add additional individual economic and psychosocial complications to HIV disease. Despite the major benefits of antiretroviral therapy on HIV outcomes, antiretroviral therapy is not sufficient to halt the complications of HCV. Nonetheless, HCV can be controlled at all stages, including prevention of infection and cure. Thus, HCV is an eradicable disease. There are significant inequalities worldwide in HCV control that could markedly constrain the impact of these measures.
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U2 - 10.1186/1758-2652-14-22
DO - 10.1186/1758-2652-14-22
M3 - Review article
C2 - 21548988
AN - SCOPUS:79955660232
SN - 1758-2652
VL - 14
JO - Journal of the International AIDS Society
JF - Journal of the International AIDS Society
IS - 1
M1 - 22
ER -