Heparin bonding on colloidal graphite surfaces

Vincent L. Gott; James D. Whiffen; Robert C. Dutton

doi:10.1126/science.142.3597.1297

Heparin bonding on colloidal graphite surfaces

Vincent L. Gott, James D. Whiffen, Robert C. Dutton

Research output: Contribution to journal › Article › peer-review

252 Scopus citations

Abstract

Experiments on clotting, both in vitro and in vivo, showed that a colloidal graphite surface, when rinsed with a cationic, surface-active agent, was capable of bonding heparin. The resistance of this graphite-heparin surface to the formation of clots was far greater than plastic or silicone surfaces in comparable studies.

Original language	English (US)
Pages (from-to)	1299-1300
Number of pages	2
Journal	Science
Volume	142
Issue number	3597
DOIs	https://doi.org/10.1126/science.142.3597.1297
State	Published - 1963
Externally published	Yes

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title = "Heparin bonding on colloidal graphite surfaces",

abstract = "Experiments on clotting, both in vitro and in vivo, showed that a colloidal graphite surface, when rinsed with a cationic, surface-active agent, was capable of bonding heparin. The resistance of this graphite-heparin surface to the formation of clots was far greater than plastic or silicone surfaces in comparable studies.",

author = "Gott, {Vincent L.} and Whiffen, {James D.} and Dutton, {Robert C.}",

year = "1963",

doi = "10.1126/science.142.3597.1297",

language = "English (US)",

volume = "142",

pages = "1299--1300",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "3597",

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TY - JOUR

T1 - Heparin bonding on colloidal graphite surfaces

AU - Gott, Vincent L.

AU - Whiffen, James D.

AU - Dutton, Robert C.

PY - 1963

Y1 - 1963

N2 - Experiments on clotting, both in vitro and in vivo, showed that a colloidal graphite surface, when rinsed with a cationic, surface-active agent, was capable of bonding heparin. The resistance of this graphite-heparin surface to the formation of clots was far greater than plastic or silicone surfaces in comparable studies.

AB - Experiments on clotting, both in vitro and in vivo, showed that a colloidal graphite surface, when rinsed with a cationic, surface-active agent, was capable of bonding heparin. The resistance of this graphite-heparin surface to the formation of clots was far greater than plastic or silicone surfaces in comparable studies.

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DO - 10.1126/science.142.3597.1297

M3 - Article

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AN - SCOPUS:37049246701

SN - 0036-8075

VL - 142

SP - 1299

EP - 1300

JO - Science

JF - Science

IS - 3597

ER -

Heparin bonding on colloidal graphite surfaces

Abstract

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