Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

T. Harris; M. Visser; L. Ferrucci; H. Resnick; R. Tracy; R. Wallace

Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

T. Harris, M. Visser, L. Ferrucci, H. Resnick, R. Tracy, R. Wallace

Research output: Contribution to journal › Article › peer-review

Abstract

Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P

Original language	English (US)
Journal	FASEB Journal
Volume	12
Issue number	5
State	Published - Mar 20 1998
Externally published	Yes

ASJC Scopus subject areas

Agricultural and Biological Sciences (miscellaneous)
General Biochemistry, Genetics and Molecular Biology
Biochemistry
Cell Biology

Cite this

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abstract = "Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P",

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year = "1998",

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T1 - Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

AU - Harris, T.

AU - Visser, M.

AU - Ferrucci, L.

AU - Resnick, H.

AU - Tracy, R.

AU - Wallace, R.

PY - 1998/3/20

Y1 - 1998/3/20

N2 - Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P

AB - Heavier BMI has been associated with higher C-reactive protein (CRP), a marker of inflammation. We investigated CRP and its primary regulatory cytokine, IL6, in relation to BMI fertile and mortality using data from the Iowa 65+ Rural Health Study on 485 healthy men and women who never smoked cigarettes (mean age=77.8, follow up=4.6 years). Heavier BMI was strongly associated with higher log-transformed plasma IL-6 (pg/ml) and CRP (mg/L) in age-adjusted models. (*P

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M3 - Article

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Heavier BMI is associated with higher IL-6 and C-reactive protein but not increased mortality

Abstract

ASJC Scopus subject areas

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