Abstract
Hashimoto's encephalopathy is a rare, imprecisely defined autoimmune neurologic syndrome associated with Hashimoto's thyroiditis that normally responds to corticosteroids. Here, we describe the case of a 55-year-old woman who presented with subacute cognitive decline and ataxia. Neoplastic, paraneoplastic, infectious, and metabolic etiologies were ruled out. Anti-TPO antibody level was markedly elevated at 966 U/mL. After one month of 60 mg/day of oral prednisone, she felt back to baseline and her Montreal Cognitive Assessment dramatically improved. Physicians should strongly consider this uncommon diagnosis in patients with rapid cognitive decline and no other clear etiology.
Original language | English (US) |
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Pages (from-to) | 72-73 |
Number of pages | 2 |
Journal | Journal of Clinical Neuroscience |
Volume | 35 |
DOIs | |
State | Published - Jan 1 2017 |
Externally published | Yes |
Keywords
- Ataxia
- Cognition
- Corticosteroids
- Creutzfeldt-Jakob disease
- Dementia
- Hashimoto's encephalopathy
ASJC Scopus subject areas
- Surgery
- Neurology
- Clinical Neurology
- Physiology (medical)