TY - JOUR
T1 - Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures
T2 - A systematic review with meta-analysis
AU - Weymann, Alexander
AU - Ali-Hasan-Al-Saegh, Sadeq
AU - Popov, Aron Frederik
AU - Sabashnikov, Anton
AU - Mirhosseini, Seyed Jalil
AU - Liu, Tong
AU - Tse, Gary
AU - Lotfaliani, Mohammadreza
AU - Ghanei, Azam
AU - Testa, Luca
AU - D’Ascenzo, Fabrizio
AU - Benedetto, Umberto
AU - Dehghan, Hamidreza
AU - Roever, Leonardo
AU - De Oliveira Sá, Michel Pompeu Barros
AU - Baker, William L.
AU - Yavuz, Senol
AU - Zeriouh, Mohamed
AU - Mashhour, Ahmed
AU - Nombela-Franco, Luis
AU - Jang, Jae Sik
AU - Meng, Lei
AU - Gong, Mengqi
AU - Deshmukh, Abhishek J.
AU - Palmerini, Tullio
AU - Linde, Cecilia
AU - Filipiak, Krzysztof J.
AU - Biondi-Zoccai, Giuseppe
AU - Calkins, Hugh
AU - Stone, Gregg W.
N1 - Funding Information:
1Department of Cardiac Surgery, University Hospital Oldenburg, European Medical School Oldenburg-Groningen, Carl von Ossietzky University Oldenburg, Oldenburg, Germany; 2Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield Hospital, Harefield Middlesex, United Kingdom; 3Cardiovascular Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 4Department of Thoracic and Cardiovascular Surgery, University Hospital Goethe University Frankfurt, Frankfurt, Germany; 5Department of Cardiothoracic Surgery, University Hospital of Cologne, Cologne, Germany; 6Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, People’s Republic of China; 7Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong; 8Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;9Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 10Department of Cardiology, IRCCS Pol. S. Donato, S. Donato Milanese, Milan, Italy; 11Division of Cardiology, Department of Medical Sciences, Città della Salute e della Scienza Hospital, University of Turin, Turin, Italy; 12Bristol Heart Institute, University of Bristol, School of Clinical Sciences, Bristol, United Kingdom; 13Department of Health Technology Assessment, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran; 14Department of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil; 15Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco (PROCAPE), Recife, Brazil; University of Pernambuco (UPE), Recife, Brazil; Nucleus of Postgraduate and Research in Health Sciences of Faculty of Medical Sciences and Biological Sciences Institute (FCM/ICB), Recife, Brazil; 16University of Connecticut/Hartford Hospital Evidence-Based Practice Centre, Hartford, CT, United States; 17Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey; 18Instituto Cardiovascular, Hospital Universitario Clínico San Carlos, Madrid, Spain; 19Department of Cardiology, Busan Paik Hospital, Inje University College of Medicine, Jin-gu, Busan, Korea; 20Mayo Clinic Heart Rhythm Section, Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States; 21Dipartimento Cardio-Toraco-Vascolare, University of Bologna, Bologna, Italy; 22Department of Cardiology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden; 231st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland; 24Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy; 25Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Italy; 26Department of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States; 27New York Presbyterian Hospital, Columbia University Medical Centre, New York, NY, United States
Publisher Copyright:
Copyright © Polskie Towarzystwo Kardiologiczne 2018.
PY - 2018
Y1 - 2018
N2 - Background: New postoperative atrial fibrillation (POAF) is one of the most critical and common complications after cardiovascular surgery precipitating early and late morbidities. Complete blood count (CBC) is an imperative blood test in clinical practice, routinely used in the examination of cardiovascular diseases. Aim: This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft (CABG), isolated valvular surgery, or a combination of these treatments. Methods: We conducted a meta-analysis of studies evaluating pre- and postoperative haematological indices in patients with POAF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. Results: A literature search of all major databases retrieved 732 studies. After screening, 22 studies were analysed including a total of 6098 patients. Pooled analysis showed preoperative platelet count (PC) (weighted mean difference [WMD] = –7.07 × 109/L and p < 0.001), preoperative mean platelet volume (MPV) (WMD = 0.53 FL and p < 0.001), preoperative white blood cell count (WBC) (WMD = 0.130 × 109/L and p < 0.001), preoperative neutrophil-to-lymphocyte ratio (NLR) (WMD = 0.33 and p < 0.001), preoperative red blood cell distribution width (RDW) (WMD = 0.36% and p < 0.001), postoperative WBC (WMD = 1.36 × 109/L and p < 0.001), and postoperative NLR (WMD = 0.74 and p < 0.001) as associated factors with POAF. Conclusions: Haematological indices may predict the risk of POAF before surgery. These easily-performed tests should definitely be taken into account in patients undergoing isolated CABG, valvular surgery, or combined procedures.
AB - Background: New postoperative atrial fibrillation (POAF) is one of the most critical and common complications after cardiovascular surgery precipitating early and late morbidities. Complete blood count (CBC) is an imperative blood test in clinical practice, routinely used in the examination of cardiovascular diseases. Aim: This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft (CABG), isolated valvular surgery, or a combination of these treatments. Methods: We conducted a meta-analysis of studies evaluating pre- and postoperative haematological indices in patients with POAF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. Results: A literature search of all major databases retrieved 732 studies. After screening, 22 studies were analysed including a total of 6098 patients. Pooled analysis showed preoperative platelet count (PC) (weighted mean difference [WMD] = –7.07 × 109/L and p < 0.001), preoperative mean platelet volume (MPV) (WMD = 0.53 FL and p < 0.001), preoperative white blood cell count (WBC) (WMD = 0.130 × 109/L and p < 0.001), preoperative neutrophil-to-lymphocyte ratio (NLR) (WMD = 0.33 and p < 0.001), preoperative red blood cell distribution width (RDW) (WMD = 0.36% and p < 0.001), postoperative WBC (WMD = 1.36 × 109/L and p < 0.001), and postoperative NLR (WMD = 0.74 and p < 0.001) as associated factors with POAF. Conclusions: Haematological indices may predict the risk of POAF before surgery. These easily-performed tests should definitely be taken into account in patients undergoing isolated CABG, valvular surgery, or combined procedures.
KW - Atrial fibrillation
KW - Cardiac surgical procedure
KW - Complete blood count
KW - Coronary artery bypass
KW - Meta-analysis
KW - Review
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U2 - 10.5603/KP.a2017.0179
DO - 10.5603/KP.a2017.0179
M3 - Article
C2 - 28980298
AN - SCOPUS:85041179321
SN - 0022-9032
VL - 76
SP - 107
EP - 118
JO - Kardiologia Polska
JF - Kardiologia Polska
IS - 1
ER -