Growth rebound after termination of stimulant drugs

Daniel J. Safer, Richard P. Allen, Evelyn Barr

Research output: Contribution to journalArticlepeer-review

81 Scopus citations


To explore further the report1 of an accelerated weight gain following termination of treatment with a stimulant drug, 66 biannual growth measurements were obtained from 1970 to 1973 on hyperactive schoolchildren who were receiving medication. All received either dextroamphetamine or methylphenidate during the school year; some also received it during the summer. The data revealed that those whose stimulant medication was terminated at the start of summer subsequently grew in weight and height at a significantly greater rate than those who continued to receive medication from June to September. In fact, discontinuance of the medication resulted in a growth rebound for this period which was 15-68% above the age-expected increment.

Original languageEnglish (US)
Pages (from-to)113-116
Number of pages4
JournalThe Journal of pediatrics
Issue number1
StatePublished - Jan 1975

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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