Granulomatous interstitial nephritis associated with bone marrow transplantation

Andrew L. Schwaderer; Lois Arend; Marc B. Lande

doi:10.1007/s00467-004-1742-3

Granulomatous interstitial nephritis associated with bone marrow transplantation

Andrew L. Schwaderer, Lois Arend, Marc B. Lande

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We describe two brothers with severe combined immunodeficiency, who presented with systemic granulomatous disease, with granulomatous interstitial nephritis as the main feature, several years following bone marrow transplantation. Neither brother had an apparent drug-induced, infectious disease or autoimmune source for the granulomatous interstitial nephritis. Both patients' renal function improved following treatment with corticosteroids. This report implicates granulomatous interstitial nephritis as a complication of bone marrow transplantation for severe combined immunodeficiency.

Original language	English (US)
Pages (from-to)	539-542
Number of pages	4
Journal	Pediatric Nephrology
Volume	20
Issue number	4
DOIs	https://doi.org/10.1007/s00467-004-1742-3
State	Published - Apr 1 2005

Keywords

Corticosteroids
Graft versus host disease
Renal granuloma
Sarcoidosis
Severe combined immunodeficiency

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Nephrology

Access to Document

10.1007/s00467-004-1742-3

Cite this

@article{c3086239ffbe404bae7e0ada8d7dda29,

title = "Granulomatous interstitial nephritis associated with bone marrow transplantation",

abstract = "We describe two brothers with severe combined immunodeficiency, who presented with systemic granulomatous disease, with granulomatous interstitial nephritis as the main feature, several years following bone marrow transplantation. Neither brother had an apparent drug-induced, infectious disease or autoimmune source for the granulomatous interstitial nephritis. Both patients' renal function improved following treatment with corticosteroids. This report implicates granulomatous interstitial nephritis as a complication of bone marrow transplantation for severe combined immunodeficiency.",

keywords = "Corticosteroids, Graft versus host disease, Renal granuloma, Sarcoidosis, Severe combined immunodeficiency",

author = "Schwaderer, {Andrew L.} and Lois Arend and Lande, {Marc B.}",

year = "2005",

month = apr,

day = "1",

doi = "10.1007/s00467-004-1742-3",

language = "English (US)",

volume = "20",

pages = "539--542",

journal = "Pediatric Nephrology",

issn = "0931-041X",

publisher = "Springer Verlag",

number = "4",

}

TY - JOUR

T1 - Granulomatous interstitial nephritis associated with bone marrow transplantation

AU - Schwaderer, Andrew L.

AU - Arend, Lois

AU - Lande, Marc B.

PY - 2005/4/1

Y1 - 2005/4/1

N2 - We describe two brothers with severe combined immunodeficiency, who presented with systemic granulomatous disease, with granulomatous interstitial nephritis as the main feature, several years following bone marrow transplantation. Neither brother had an apparent drug-induced, infectious disease or autoimmune source for the granulomatous interstitial nephritis. Both patients' renal function improved following treatment with corticosteroids. This report implicates granulomatous interstitial nephritis as a complication of bone marrow transplantation for severe combined immunodeficiency.

AB - We describe two brothers with severe combined immunodeficiency, who presented with systemic granulomatous disease, with granulomatous interstitial nephritis as the main feature, several years following bone marrow transplantation. Neither brother had an apparent drug-induced, infectious disease or autoimmune source for the granulomatous interstitial nephritis. Both patients' renal function improved following treatment with corticosteroids. This report implicates granulomatous interstitial nephritis as a complication of bone marrow transplantation for severe combined immunodeficiency.

KW - Corticosteroids

KW - Graft versus host disease

KW - Renal granuloma

KW - Sarcoidosis

KW - Severe combined immunodeficiency

UR - http://www.scopus.com/inward/record.url?scp=15344345195&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15344345195&partnerID=8YFLogxK

U2 - 10.1007/s00467-004-1742-3

DO - 10.1007/s00467-004-1742-3

M3 - Article

C2 - 15690193

AN - SCOPUS:15344345195

SN - 0931-041X

VL - 20

SP - 539

EP - 542

JO - Pediatric Nephrology

JF - Pediatric Nephrology

IS - 4

ER -

Granulomatous interstitial nephritis associated with bone marrow transplantation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this