Gradient-enhanced heteronuclear correlation spectroscopy: Theory and experimental aspects

Jesús Ruiz-Cabello, Geerten W. Vuister, Chrit T.W. Moonen, Peter van Gelderen, Jack S. Cohen, Peter C.M. van Zijl

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A detailed theoretical and experimental treatment is given for gradient-enhanced heteronuclear correlation spectroscopy. Both multiple-quantum and single-quantum sequences are described. In addition to a comparison with conventional experiments using phase cycling, the effects of different gradient combinations are examined with respect to artifacts occurring in the heteronuclear dimension. The influence of gradient performance and diffusion on sensitivity is discussed. Approaches to attain phase-sensitive spectra are also analyzed.

Original languageEnglish (US)
Pages (from-to)446-466
Number of pages21
JournalJournal of Magnetic Resonance
Issue number2
StatePublished - Dec 2011
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics


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