TY - JOUR
T1 - Governing with public engagement
T2 - an anticipatory approach to human genome editing
AU - Barlevy, Dorit
AU - Juengst, Eric
AU - Kahn, Jeffrey
AU - Moreno, Jonathan
AU - Lambert, Lauren
AU - Charo, Alta
AU - Chneiweiss, Hervé
AU - Farooque, Mahmud
AU - Guston, David H.
AU - Hyun, Insoo
AU - Knoepfler, Paul S.
AU - Selin, Cynthia
AU - Wilbanks, Rebecca
AU - Zaghlula, Manar
AU - Scott, Christopher Thomas
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/8/1
Y1 - 2024/8/1
N2 - In response to calls for public engagement on human genome editing (HGE), which intensified after the 2018 He Jiankui scandal that resulted in the implantation of genetically modified embryos, we detail an anticipatory approach to the governance of HGE. By soliciting multidisciplinary experts’ input on the drivers and uncertainties of HGE development, we developed a set of plausible future scenarios to ascertain publics values—specifically, their hopes and concerns regarding the novel technology and its applications. In turn, we gathered a subset of multidisciplinary experts to propose governance recommendations for HGE that incorporate identified publics’ values. These recommendations include: (1) continued participatory public engagement; (2) international harmonization and transparency of multiple governance levers such as professional and scientific societies, funders, and regulators; and (3) development of a formal whistleblower framework.
AB - In response to calls for public engagement on human genome editing (HGE), which intensified after the 2018 He Jiankui scandal that resulted in the implantation of genetically modified embryos, we detail an anticipatory approach to the governance of HGE. By soliciting multidisciplinary experts’ input on the drivers and uncertainties of HGE development, we developed a set of plausible future scenarios to ascertain publics values—specifically, their hopes and concerns regarding the novel technology and its applications. In turn, we gathered a subset of multidisciplinary experts to propose governance recommendations for HGE that incorporate identified publics’ values. These recommendations include: (1) continued participatory public engagement; (2) international harmonization and transparency of multiple governance levers such as professional and scientific societies, funders, and regulators; and (3) development of a formal whistleblower framework.
KW - anticipatory governance
KW - human genome editing
KW - public engagement
UR - http://www.scopus.com/inward/record.url?scp=85199172976&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85199172976&partnerID=8YFLogxK
U2 - 10.1093/scipol/scae010
DO - 10.1093/scipol/scae010
M3 - Article
C2 - 39035203
AN - SCOPUS:85199172976
SN - 0302-3427
VL - 51
SP - 680
EP - 691
JO - Science and Public Policy
JF - Science and Public Policy
IS - 4
ER -