Glycans in Inflammation

Anabel Gonzalez-Gil; Ronald L. Schnaar

doi:10.1016/B978-0-12-821618-7.00007-9

Glycans in Inflammation

Anabel Gonzalez-Gil, Ronald L. Schnaar

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Acute inflammation is how the body responds to mitigate infection and injury. It is characterized by an initiation phase that recruits immune cells to the affected site where they cross the blood vessel wall into the tissue to kill infectious agents and/or respond to injury. Inflammation is highly regulated so that it is resolved before excessive tissue damage occurs. Every step, from initiation to execution to resolution involves glycans and complementary glycan binding proteins (lectins). Here we summarize some of the essential ways in which glycans drive the inflammatory response.

Original language	English (US)
Title of host publication	Encyclopedia of Cell Biology
Subtitle of host publication	Volume 1-6, Second Edition
Publisher	Elsevier
Pages	338-348
Number of pages	11
Volume	4
ISBN (Electronic)	9780128216248
DOIs	https://doi.org/10.1016/B978-0-12-821618-7.00007-9
State	Published - Jan 1 2022

Keywords

C-type lectin
Damage-associated molecular pattern (DAMP)
Eosinophil
Galactose
Galectin
Hyaluronic acid
Mannose
Neutrophil
Pathogen-associated molecular pattern (PAMP)
Pattern recognition receptor (PRR)
Selectin
Sialic acid
Siglec

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-821618-7.00007-9

Cite this

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KW - Damage-associated molecular pattern (DAMP)

KW - Eosinophil

KW - Galactose

KW - Galectin

KW - Hyaluronic acid

KW - Mannose

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KW - Pathogen-associated molecular pattern (PAMP)

KW - Pattern recognition receptor (PRR)

KW - Selectin

KW - Sialic acid

KW - Siglec

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M3 - Chapter

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EP - 348

BT - Encyclopedia of Cell Biology

PB - Elsevier

ER -

Glycans in Inflammation

Abstract

Keywords

ASJC Scopus subject areas

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