Glucosamine and chondroitin sulfate are effective in the management of osteoarthritis

David S. Hungerford, Lynne C. Jones

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


The use of glucosamine and chondroitin sulfate for the symptomatic treatment of osteoarthritis has been a subject of controversy for several reasons. First, the medical community in general took offense at the title of Theodosakis' book, The Arthritis Cure. Second, the medical community is becoming divided into "traditional" and "alternative" camps with deep skepticism between them. Third, the whole nutraceutical industry is essentially unregulated, with manufacturers making outrageous claims on products that have never been tested at all, are often of poor quality, and occasionally lacking in any active ingredient. However, for the nutriceuticals evaluated here, there is abundant in vitro, in vivo, animal clinical, and human clinical evidence of both their efficacy and safety. They deserve a prominent place in the armamentarium of nonsurgical treatment of osteoarthritis.

Original languageEnglish (US)
Pages (from-to)5-9
Number of pages5
JournalJournal of Arthroplasty
Issue number3 SUPPL. 1
StatePublished - Apr 2003
Externally publishedYes


  • Cartilage
  • Chondroitin sulfate
  • Glucosamine
  • Nutraceuticals
  • Osteoarthritis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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