Getaway car: Fungal HscA steers human phagosomal p11 into an escape route

Emma Camacho, Carolina Coelho

Research output: Contribution to journalComment/debatepeer-review

Abstract

In this issue of Cell Host & Microbe, Jia and colleagues discover how the human p11 (s100A10)-Anxa2 heterodimer drives sorting of microbial phagosomes into recycling versus degradative pathways. In a remarkable evolutionary arms race, the Aspergillus fumigatus protein HscA latches to p11 to steer its phagosome away from fungal killing.

Original languageEnglish (US)
Pages (from-to)324-327
Number of pages4
JournalCell Host and Microbe
Volume31
Issue number3
DOIs
StatePublished - Mar 8 2023

ASJC Scopus subject areas

  • Virology
  • Parasitology
  • Microbiology

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