TY - JOUR
T1 - Geographical distribution and ecological niche modeling of the etiological agents of human sporotrichosis in Venezuela
AU - Barreto, Laura
AU - Velásquez, Grisel
AU - Mendoza, Mireya
AU - Camacho, Emma
AU - Goncalves, Estefany
AU - Rodríguez, Sabrina
AU - Niño-Vega, Gustavo A.
N1 - Funding Information:
The data here presented were part of the M.Sc. thesis work of LB at IVIC. This work was partially supported by Research Project N° 112 to SR and GAN-V from the Instituto Venezolano de Investigaciones Cientificas (IVIC, Venezuela).
Publisher Copyright:
© 2020, Sociedade Brasileira de Microbiologia.
PY - 2021/3
Y1 - 2021/3
N2 - The geographical distribution and ecological niche of the two circulating species of the Sporothrix genus in Venezuela was established. For this, 68 isolates of Sporothrix spp. from patients of different regions of the country were analyzed. A molecular taxonomy analysis was conducted using a fragment of the calmodulin gene (CAL), and ITS regions, confirming the presence of S. schenckii (62%) and S. globosa (38%). Computational models of ecological niche for each species were obtained by the maximum entropy method using the MaxEnt software, which predicted the best environmental conditions for the presence of the two species. These models predict that the main variables influencing the presence of S. schenckii were altitude and annual mean temperature, while for S. globosa, the more influent variable was the land use, with 82% of S. globosa located at urban areas vs 56% for S. schenckii. The results here presented could contribute to understand the specific environmental factors that might modulate the occurrence of Sporothrix spp. as well as its transmission. To our knowledge, our analyses show for the first time Sporothrix spp.–specific ecological niche data, a valuable tool to promote evidence-based public health policymaking within endemic areas of sporotrichosis.
AB - The geographical distribution and ecological niche of the two circulating species of the Sporothrix genus in Venezuela was established. For this, 68 isolates of Sporothrix spp. from patients of different regions of the country were analyzed. A molecular taxonomy analysis was conducted using a fragment of the calmodulin gene (CAL), and ITS regions, confirming the presence of S. schenckii (62%) and S. globosa (38%). Computational models of ecological niche for each species were obtained by the maximum entropy method using the MaxEnt software, which predicted the best environmental conditions for the presence of the two species. These models predict that the main variables influencing the presence of S. schenckii were altitude and annual mean temperature, while for S. globosa, the more influent variable was the land use, with 82% of S. globosa located at urban areas vs 56% for S. schenckii. The results here presented could contribute to understand the specific environmental factors that might modulate the occurrence of Sporothrix spp. as well as its transmission. To our knowledge, our analyses show for the first time Sporothrix spp.–specific ecological niche data, a valuable tool to promote evidence-based public health policymaking within endemic areas of sporotrichosis.
KW - Ecological niche modeling
KW - MaxEnt
KW - Sporothrix globosa
KW - Sporothrix schenckii
KW - Sporotrichosis
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U2 - 10.1007/s42770-020-00306-0
DO - 10.1007/s42770-020-00306-0
M3 - Article
C2 - 32696418
AN - SCOPUS:85088360775
SN - 1517-8382
VL - 52
SP - 63
EP - 71
JO - Brazilian Journal of Microbiology
JF - Brazilian Journal of Microbiology
IS - 1
ER -