Genomics of fibromyalgia

Nada Lukkahatai, Leorey N. Saligan

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter describes investigations that explored the genomic correlates of fibromyalgia. Significance and prevalence rates are reviewed and definitions are discussed within the context of the need to develop case definitions and phenotypes to advance the science and management of fibromyalgia. Underlying mechanisms and several clinical practice guidelines are presented. A summary of recommendations regarding assessment and management of fibromyalgia, drawn from the guidelines, is listed with particular emphasis on the co-management of co-occurring symptoms and conditions such as deconditioning and muscle weakness, lack of energy, pain, emotional distress, cognitive impairment, sleep disturbance/insomnia, and nutrition-related issues. The chapter concludes with a brief discussion about the significance of these genomic correlates of fibromyalgia recommending potential research topics to pursue in order to fill the existing gaps in knowledge.

Original languageEnglish (US)
Title of host publicationGenomics of Pain and Co-Morbid Symptoms
PublisherSpringer International Publishing
Number of pages9
ISBN (Electronic)9783030216573
ISBN (Print)9783030216566
StatePublished - Jan 1 2020


  • Central pain disorder
  • Fibromyalgia
  • Generalized pain

ASJC Scopus subject areas

  • Nursing(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)


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