Abstract
The investigation of the genetic basis of refractive error and myopia entered a new stage with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many ethnic groups have been published over the years, providing new insight into the genetic architecture and pathophysiology of refractive error. This is a review of the GWAS published to date, the main lessons learned, and future possible directions of genetic studies of myopia and refractive error.
Original language | English (US) |
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Pages (from-to) | 3344-3351 |
Number of pages | 8 |
Journal | Investigative Ophthalmology and Visual Science |
Volume | 55 |
Issue number | 5 |
DOIs | |
State | Published - May 29 2014 |
Keywords
- GWAS
- Genetic architecture
- Refractive error
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience