TY - JOUR
T1 - Genetic control of ventilation
T2 - What are we learning from murine models?
AU - Tankersley, Clarke G.
PY - 1999/1/1
Y1 - 1999/1/1
N2 - Advances in human and mouse genomes are revolutionizing research in lung biology and pulmonary medicine. Genomic strategies are available that link functional variation to molecular structure, and these approaches are currently being applied to the study of ventilatory control mechanisms. In this review, the author discusses the functional data obtained from inbred murine models in which genetic mutations and polymorphisms play a role in altered breathing. At the conclusion of this review, the author emphasizes the relatively small number of studies that have incorporated the use of genomics to link differential ventilatory function to molecular structure. Curr Opin Pulm Med 1999, 5:344-348
AB - Advances in human and mouse genomes are revolutionizing research in lung biology and pulmonary medicine. Genomic strategies are available that link functional variation to molecular structure, and these approaches are currently being applied to the study of ventilatory control mechanisms. In this review, the author discusses the functional data obtained from inbred murine models in which genetic mutations and polymorphisms play a role in altered breathing. At the conclusion of this review, the author emphasizes the relatively small number of studies that have incorporated the use of genomics to link differential ventilatory function to molecular structure. Curr Opin Pulm Med 1999, 5:344-348
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U2 - 10.1097/00063198-199911000-00004
DO - 10.1097/00063198-199911000-00004
M3 - Article
C2 - 10570734
AN - SCOPUS:0033227793
SN - 1070-5287
VL - 5
SP - 344
EP - 348
JO - Current opinion in pulmonary medicine
JF - Current opinion in pulmonary medicine
IS - 6
ER -