Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis

Marzieh Akhlaghpour, Talin Haritunians, Shyam K. More, Lisa S. Thomas, Dalton T. Stamps, Shishir Dube, Dalin Li, Shaohong Yang, Carol J. Landers, Emebet Mengesha, Hussein Hamade, Ramachandran Murali, Alka A. Potdar, Andrea J. Wolf, Gregory J. Botwin, Michelle Khrom, Ashwin N. Ananthakrishnan, William A. Faubion, Bana Jabri, Sergio A. LiraRodney D. Newberry, Robert S. Sandler, R. Balfour Sartor, Ramnik J. Xavier, Steven R. Brant, Judy H. Cho, Richard H. Duerr, Mark G. Lazarev, John D. Rioux, L. Philip Schumm, Mark S. Silverberg, Karen Zaghiyan, Phillip Fleshner, Gil Y. Melmed, Eric A. Vasiliauskas, Christina Ha, Shervin Rabizadeh, Gaurav Syal, Nirupama N. Bonthala, David A. Ziring, Stephan R. Targan, Millie D. Long, Dermot P.B. Mcgovern, Kathrin S. Michelsen

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Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology